Ketamine has gained attention in recent years not only as a treatment for depression, anxiety, and PTSD, but also for its unique ability to shift the way we experience our own thoughts and emotions. At therapeutic doses, ketamine can quiet the intensity of emotional reactions, creating a kind of mental “stillness” that allows thoughts to be observed more objectively.

When we talk about ketamine’s ability to reduce depression and anxiety, the focus is usually on humans—and for good reason. But fascinating insights are also coming from an unlikely source: zebrafish.

If you've ever felt out of sorts—tired, anxious, moody, or foggy—without any clear explanation, your hormones could be the missing piece of the puzzle. Hormonal health isn’t just about physical functions like metabolism and reproduction; it plays a direct and powerful role in mental and emotional well-being.

At Well3, we believe that small daily habits can spark meaningful change in your life. That’s why we’re excited to introduce our newest creation: the Gratitude and Inspiration app—a simple, powerful tool designed to help you build a gratitude practice in just one minute a day.

GLP-1 medications like semaglutide and tirzepatide have changed the game for weight loss. But while these medications are powerful tools, they’re not a standalone solution. The best—and most sustainable—results happen when you combine them with changes in how you eat, move, and manage stress.

GLP-1 medications like semaglutide (Ozempic®, Wegovy®) and tirzepatide (Mounjaro®) have been life-changing for many people working toward sustainable weight loss. But like any powerful tool, they come with an adjustment period.

Post-Traumatic Stress Disorder (PTSD) is one of the most complex and difficult mental health conditions to treat. Affecting veterans, first responders, survivors of abuse, and many others, PTSD can disrupt daily life through flashbacks, insomnia, emotional numbness, and intense anxiety.

Ketamine therapy is changing the equation. Known for its rapid-acting antidepressant effects, ketamine is offering new hope for people who need relief now—not months from now. But how does it compare to traditional treatments? Let’s break it down.

Originally developed to treat type 2 diabetes, these medications have quickly gained attention for their ability to support sustainable, medically guided weight loss. But how do they actually work? And how are they different from traditional methods?

Ketamine therapy offers a new and powerful option for professionals looking to reset, heal, and regain clarity. Backed by scientific research and real-world success stories, ketamine is quickly becoming a go-to for those seeking fast and effective mental health support.

Learn how semaglutide and tirzepatide help reduce sugar cravings, reset your gut, and make it easier to stick to a healthy lifestyle for lasting weight loss.

Discover how ketamine nasal spray and troches help repair stress-damaged brain circuits. Fast, science-backed relief from burnout, anxiety, and exhaustion.

Over the past few years, GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed diabetes management and weight loss treatment. However, these medications come with a significant price tag—especially in the United States—where costs are often several times higher than in other countries.

Scientists have made an important breakthrough in understanding exactly how ketamine works in the brain, potentially explaining why it's so effective for treating depression. This research, conducted at Cold Spring Harbor Laboratory and published in Neuron, provides detailed insights into ketamine's interaction with brain receptors that could lead to better treatments in the future.

Trauma can be one of life's most profound teachers. Through our wounds, we often develop deeper empathy, resilience, and understanding of both ourselves and others. However, when trauma's lessons become trapped in our nervous system, they can prevent us from fully engaging with life and experiencing joy, connection, and peace in the present moment.

Post-Traumatic Stress Disorder (PTSD) can be a relentless battle, leaving people stuck in cycles of fear, anxiety, and distress. While traditional treatments like therapy and antidepressants help some, many individuals continue to struggle. A recent study, called OKTOP, explored an alternative approach—using low-dose oral ketamine to treat PTSD. The results offer a glimpse of hope for those seeking new options.

Singapore is renowned for having some of the strictest drug laws in the world. Its zero-tolerance policies, mandatory death penalty for large-scale drug trafficking, and severe penalties for drug consumption have shaped its reputation as a global leader in the fight against drug abuse. However, amidst its tough stance, Singapore is also making headlines for its groundbreaking use of ketamine—a substance with a reputation for recreational drug use—in treating depression.

Imagine trying to move your hand to pick up a cup, but your brain’s signals don’t quite match the movement your body makes. This mismatch is a significant challenge for people with Parkinson’s disease and a side effect of its most common treatment, levodopa. Scientists are exploring innovative ways to address these movement difficulties, and a new study suggests that ketamine, in very low doses, could be a surprising ally.

“Just keep swimming,” Dory—the lovable fish from Finding Nemo—famously said. It’s a mantra of persistence and optimism, encouraging us to keep moving forward despite challenges. But what happens when even Dory might feel like giving up? A recent study in Neuron reveals how the brain responds to failure and how ketamine, a surprising player, can help reignite the will to persevere.

This study investigates how ketamine, a drug known for its rapid and long-lasting antidepressant effects, helps repair brain connections in a mouse model of chronic stress. Researchers focused on specific proteins, called planar cell polarity (PCP) proteins, which play a vital role in maintaining healthy communication between brain cells.